Date published: 2025-10-10

021-6093-6350

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β-defensin 125激活剂

These peptides are characterized by their structure, which typically includes a core of beta-sheet regions stabilized by disulfide bonds. This structure allows β-defensins to interact with and permeate the lipid membranes of pathogens, leading to their antimicrobial activity. Human β-defensins also possess immunomodulatory functions, such as recruiting immune cells to the site of infection and modulating cell signaling pathways involved in inflammation and immune responses.β-defensins are predominantly expressed in epithelial tissues that interface with the external environment, including the skin, respiratory, gastrointestinal, and urogenital tracts. This strategic expression pattern enables them to respond rapidly to microbial invasion at these critical barriers.

The expression of β-defensins can be induced by the presence of bacteria and other pathogens, as well as by cytokines and inflammatory mediators. This inducible nature allows for a rapid and localized increase in peptide concentration at infection sites, enhancing the body's ability to combat infectious agents.Should "β-defensin 125" be a member of this family, it would be expected to share these defining antimicrobial and immunomodulatory properties, contributing to the host's protective mechanisms against a wide array of pathogens.

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